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Soy and levothyroxine

In the body: Soy can reduce how much levothyroxine, a thyroid medicine, the gut absorbs.

Not rated by dose: a flag on 3 reviewed foods, among them calcium-set tofu, Edamame, cooked and Soy drink, unsweetened, fortified.

For some people. Allergies, medicines and medical conditions: a flag for the people the source names, no wider.

All hazards

The reference value and where it comes from

  • The agency’s figureno agency dose value
  • Basisdrug label: soy can reduce levothyroxine absorption
  • Source SYNTHROID

Reviewed foods that carry it

3 reviewed foods carry it; none is rated by dose.

How often you can eat it

No food here is rated by dose. Each line says why it’s listed: a flag for the people the source names, advice on handling it, or context.

Flags and context, not rated by dose

  • Edamame, cooked

    Worth knowing

    SYNTHROID · grade A

    How it’s rated

    Flagged for people on levothyroxine: soy foods may reduce its absorption. The US label names soybean flour and soybean-based infant formula, not edamame, so applying it to whole green soybeans is by extension, and the label gives no quantity; people on levothyroxine are told to keep soy away from the dose.

    Intake: not applicable (flag)

    Measured on: not stated in the draft

  • SYNTHROID · grade A

    How it’s rated

    Flagged for people on levothyroxine: the US label says soybean flour, among other foods, may bind the drug and decrease its absorption. It names soybean flour and soy-based infant formula rather than soy drink, so the effect here is by extension, and the label gives no quantity.

    Intake: not applicable (flag)

    Measured on: not stated in the draft

  • SYNTHROID · grade A

    How it’s rated

    Context, not a flag: the levothyroxine label names soybean flour, not tofu, and its 4-hour rule covers calcium supplements, not foods.

    Intake: not applicable (flag)

    Measured on: person-specific (drug interaction)

Sources