Watercress PEITC and CYP2E1
In the body: no agency opinion we hold names an effect at the amounts found in food, so it is shown for context, not rated.
Not rated by dose: a flag on one reviewed food, watercress.
Background. Shown, not scored: no dose basis at normal intake, a classification rather than a risk, or legal limits only.
The reference value and where it comes from
- The agency’s figureno agency dose value
- Basiswatercress PEITC inhibits CYP2E1 (study, no agency advice)
- Source ?PubMed 9728894
Reviewed foods that carry it
1 reviewed food carries it; none is rated by dose.
How often you can eat it ?
No food here is rated by dose. Each line says why it’s listed: a flag for the people the source names, advice on handling it, or context.
Flags and context, not rated by dose
Watercress, rawContext
PubMed 9728894 · grade B ?
How it’s rated
Context only. The study abstract names no compound (the link to phenethyl isothiocyanate does not come from a source read); no agency basis and no drug label naming watercress was found, so no flag. A 2002 study found no important effect on how fast alcohol is cleared.
Intake: not applicable (flag) · Level in the food: 56 % increase in chlorzoxazone AUC (single human study, n = 10)
Measured on: single ingestion of 50 g watercress homogenate, 10 healthy volunteers; chlorzoxazone is a CYP2E1 probe
Sources
- Leclercq I, Desager JP, Horsmans Y. Inhibition of chlorzoxazone metabolism, a clinical probe for CYP2E1, by a single ingestion of watercress. Clin Pharmacol Ther 1998;64(2):144-9. · doi:10.1016/S0009-9236(98)90147-3 · PMID 9728894
pmid:9728894· abstract only · Publisher copyright